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朱闻君
来源:    时间:2019/09/10    编辑:swzy2    点击:

个人简介模板

姓名:

朱闻君    

办公地址:

武汉轻工大学生化楼705/707

联系电话:

13545201520

电子邮箱:

82862108@qq.com

简要描述

本实验室主要从事:(1)植物病害真菌灰葡萄孢(Botrytis cinerea)分泌蛋白的功能研究;(2)十字花科植物炭疽菌希金斯刺盘孢(Colletotrichum higginsianum)致病相关基因的功能研究;(3)植物与病原微生物互作的分子机理研究;(4)药食两用真菌茯苓(Wolfiporia cocos)的基因功能研究。

教育经历

2014/10 -2017/02Tel-Aviv   UniversityDepartment of Molecular Biology and Ecology of Plants, Faculty   of Life Science,博士后;

2006/09 -2012/12,华中农业大学,植物科技学院,植物病理,博士;

2002/09 -2006/06,华中师范大学,生命科学院,生物技术,本科学士。

工作经历

201410-20172月:以色列特拉维夫大学 (Tel-Aviv   University),博士后,从事:1)植物病害真菌灰葡萄孢(Botrytis cinerea)致病相关分泌蛋白的筛选及其致病机理研究;(2)植物内生菌诱导植物抗逆机理的研究;

20195至今:武汉轻工大学,生物与制药工程学院,副教授;

201212—20195月:武汉轻工大学,生物与制药工程学院,讲师。

研究方向:

1)植物病害真菌灰葡萄孢(Botrytis cinerea)分泌蛋白的功能研究;(2)十字花科植物炭疽菌希金斯刺盘孢(Colletotrichum higginsianum)致病相关基因的功能研究;(3)植物与病原微生物互作的分子机理研究;(4)药食两用真菌茯苓(Wolfiporia cocos)的基因功能研究。

主要承担的科研项目:

1主持国家自然科学基金面上项目:弱活性小分子分泌蛋白BC1G_01444在灰葡萄孢与植物互作过程中的功能机理研究(31972215),57万,2020.01-2023.12

2主持国家自然科学基金青年科学基金项目:致病相关分泌蛋白BC1G_08363BC1G_15201在灰葡萄孢致病过程中的作用及其机理研究(31501587),22.8万,2016.01-2018.12

3合作参与国家自然科学基金面上项目:甾醇氧乙酰基转移酶(SOAT)在茯苓酸生物合成途径中的功能解析(81872948),57, 2019.01-2022.12

4合作参与2018年度国家自然科学基金委员会与以色列科学基金会合作研究项目:利用真菌病毒研究葡萄孢和植物的相互作用(31861143043),160万,201911-20211231日。

5主持湖北省农业科学院植保土肥研究所开放基金课题:小分子分泌蛋白BC1G_01016在灰葡萄孢与植物互作过程中的功能机理研究(2018ZTSJJ14),4万,201810-20209月。

6主持横向项目:中药材及其致病菌组学相关研究(whpu-2018-cg-138),5万,201911-20201231日。

代表性论文与著作

通讯作者(*)或第一作者:

1.           Zhu W, Xu X, Peng F, Yan D, Zhang S, Xu R, Wu J, Li X, Wei W*, Chen W*   (2019) The cyclase-associated protein ChCAP is important for   regulation of hyphal growth, appressorial development, penetration,   pathogenicity, conidiation, intracellular cAMP level, and stress tolerance in   Colletotrichum higginsianum. Plant Sci 283: 1–10.

2.           Zhu W*, Wei W, Zhang S, Zheng Y, Chen P, Xu X   (2018) The phosphatome of medicinal and edible fungus Wolfiporia   cocos. Curr Microbiol 75: 124–131.

3.           Zhu W, Ronen M, Gur Y, Minz-Dub A, Masrati G, Ben-Tal N, Sharon I,   Savidor A, Eizner E, Valerius O, Braus G, Bowler K, Bar-Peled M, Sharon A* (2017)   BcXYG1, a secreted xyloglucanase from Botrytis cinerea, triggers both   cell death and plant immune responses. Plant Physiol 175:   438-456.

4.           Zhu W*, Wei W, Wu Y, Zhou Y, Peng F, Zhang S,   Chen P, Xu X (2017) BcCFEM1, a CFEM domain-containing protein with   putative GPI-anchored site, is involved in pathogenicity, conidial production   and stress tolerance in Botrytis cinerea. Front Microbiol 8:   1807.

5.           Zhu W*, Zhou M, Xiong Z, Peng F, Wei W* (2017)   The cAMP-PKA signaling pathway regulates pathogenicity, hyphal growth,   appressorial formation, conidiation, and stress tolerance in Colletotrichum   higginsianum. Front Microbiol 8: 1416.

6.           Wei W, Shu S, Zhu W*, Xiong Y, Peng F (2016) The   kinome of edible and medicinal fungus Wolfiporia cocos. Front   Microbiol 7: 1495.

7.           Wei W, Xiong Y, Zhu W*, Wang N, Yang G, Peng F (2016) Colletotrichum   higginsianum mitogen-activated protein kinase ChMK1: role in growth, cell   wall integrity, colony melanization and pathogenicity. Front Microbiol   7: 1212.

8.           Zhang S, Hu B, Wei W, Xiong Y, Zhu   W*, Peng F, Yu Y, Zheng Y, Chen P* (2016) De novo   analysis of Wolfiporia cocos transcriptome to reveal the   differentially expressed carbohydrate-active enzymes (CAZymes) genes during   the early stage of sclerotial growth. Front Microbiol   7: 83.

9.           Wu Y, Zhu W (Co-first author), Wei W, Zhao X,   Wang Q, Zeng W, Zheng Y, Chen P*, Zhang S* (2016) De novo   assembly and transcriptome analysis of sclerotial development in Wolfiporia   cocos. Gene 588:   149-155.

10.       Sun Q, Wei W, Zhu W*, Zhang S, Song J, Zheng Y, Chen P* (2015) Genetic   diversity of Chinese Wolfiporia cocos cultivars revealed by phenotypic   traits and ISSR markers. Mycol Progress 14: 61.

11.       Sun Q, Wei W, Zhao J, Song J, Peng F, Zhang S, Zheng Y, Chen P, Zhu W* (2015) An efficient PEG/CaCl2-mediated transformation   approach for the medicinal fungus Wolfiporia cocos. J Microbiol Biotechn 25: 1528-1531.

12.       Zhu W, Wei W, Fu Y, Cheng J, Xie J, Li G, Yi X, Kang Z, Dickman MB,   Jiang D* (2013) A secretory protein of necrotrophic fungus Sclerotinia   sclerotiorum that suppresses host resistance. PLoS ONE 8:   e53901.

非通讯作者或非第一作者:

1.         Doehlemann G*, Ökmen B, Zhu   W, Sharon A (2017) Plant pathogenic fungi. Microbiol Spectrum   5(1): FUNK-0023-2016. doi: 10.1128/microbiolspec.FUNK-0023-2016.

2.         Liu X, Wei W*, Zhu W, Su L, Xiong Z, Zhou M, Zheng Y, Zhou D-X* (2017) Histone   deacetylase AtSRT1 regulates metabolic flux and stress response in Arabidopsis.   Mol Plant. 10: 1510-1522.

3.         Yu Y*, Xiao J, Zhu W, Yang Y, Mei J, Bi C, Qian W, Qing L, Tan W (2017) Ss-Rhs1,   a secretory Rhs repeat-containing protein, is required for the virulence of Sclerotinia   sclerotiorum. Mol Plant Pathol 18: 1052-1061.

4.         Eizner E, Ronen M, Gur Y, Gavish A, Zhu W,   Sharon A* (2017) Characterization of Botrytis-plant   interactions using PathTrack© - an automated system for dynamic   analysis of disease development. Mol Plant Pathol 18: 503-512.

5.         Wei W, Zhu W, Cheng J, Xie J, Jiang D, Li G, Chen W, Fu Y* (2016) Nox   complex signal and MAPK cascade pathway are cross-linked and essential for   pathogenicity and conidiation of mycoparasite Coniothyrium minitans. Sci   Rep 6: 24325.

6.         Shlezinger N, Israeli M, Mochly E, Oren-Young L, Zhu W,   Sharon A* (2016) Translocation from nuclei to cytoplasm is necessary   for anti A-PCD activity and turnover of the Type II IAP BcBir1. Mol   Microbiol 99: 393-406.

7.         Zhang S, Wang R, Zeng W, Zhu   W, Zhang X, Wu C, Song J, Zheng Y, Chen P* (2015) Resource investigation of traditional   medicinal plant Panax japonicus (T.Nees) C.A. Mey and its varieties in   China. J Ethnopharmacol 166: 79-85.

8.         Zhang S, Wu Y, Jin J, Hu B, Zeng W, Zhu W, Zheng   Y*, Chen P* (2015) De novo characterization of Panax   japonicus C. A. Mey transcriptome and genes related to triterpenoi   saponin biosynthesis. Biochem Bioph Res Co 466: 450-455.

9.         Tang J, Nie J, Li D, Zhu   W, Zhang S, Ma F, Sun Q, Song J, Zheng Y, Chen P* (2014)   Characterization and antioxidant activities of degraded polysaccharides from Poria   cocos sclerotium. Carbohyd Polym 105: 121-126.

10.   Yang X, Wang R, Zhang S, Zhu   W, Tang J, Liu J, Chen P*, Zhang D*,   Zheng Y (2014) Polysaccharides from Panax japonicus C.A. Meyer   and their antioxidant activities. Carbohyd Polym 101: 386-391.

11.   Wei W, Zhu W, Cheng J, Xie J, Li B, Jiang D, Li G, Yi X, Fu Y* (2013)   CmPEX6, a gene involved in peroxisome biogenesis, is essential for parasitism   and conidiation by sclerotial parasite Coniothyrium minitans. Appl   Environ Microb 79: 3658-3666.

专利成果:

获奖:

(1)   Post-Doctoral Program for outstanding Post-Doctoral Researchers from China   & India 2016-2017;

(2)   Post-Doctoral Program for outstanding Post-Doctoral Researchers from China   & India 2015-2016;

(3)   Post-Doctoral Program for outstanding Post-Doctoral Researchers from China   & India 2014-2015  

其它:

 

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