办公地址：

食品科技楼615室

联系电话：

027-83956793

电子邮箱：

chaohongjun[AT] whpu.edu.cn

个人简介

 晁红军，男，2013年于中科院武汉病毒研究所获博士学位，留所工作。2018年7月来武汉轻工大学工作。目前主要从事有机污染物的微生物分解代谢和转录调控机制的研究。主持一项湖北省科技厅自然科学基金（No.2023AFB884），完成一项国家自然科学基金青年（No.31400068）和一项国家自然基金面上（No.31770119)。已发表SCI 收录论文40余篇，其中第一和通讯作者15篇。担任Applied and Environmental Microbiology， Environmental Microbiology，Journal of Applied Microbiology， International Biodeterioration and Biodegradation, Frontiers in Microbiology, BioMed Research International等杂志审稿人，国家自然科学基金委员会面上类项目通讯评审、重点类项目通讯评审专家和全国研究生教育评估监测专家库专家等。曾获 “简浩然环境微生物基金”优秀论文奖，全国微生物遗传学学术研讨会博士论坛二等奖，中国科学院武汉教育基地昌华奖学金暨武汉分院院长奖学金特别奖，中国科学院朱李月华优秀博士生奖学金获奖。指导本科生获得全国大学生生命科学竞赛国赛一等奖（科学探究类）和国赛三等奖（创新创业类），指导研究生获得校级优秀毕业生和校级优秀毕业论文，多名研究生继续攻读博士研究生。

工作经历

2018/07-至今，武汉轻工大学，讲师，副教授

2013/07-2018/06，中国科学院武汉病毒研究所，助理研究员

研究方向：

1．微生物分解代谢，主要从事有机污染物的微生物分解代谢和转录调控机制的研究。

2．微生物环保菌剂的开发与利用。

主要承担的科研项目：

1. 湖北省科技厅自然科学基金（面上项目：2023AFB884），根瘤菌CHJ608中2,6-二叔丁基苯酚分解代谢途径的研究，主持，执行年限：2023.06-2025.06；

2. 武汉轻工大学校立科研项目（2023Y14），红球菌CHJ02中3,5-二甲基苯酚分解代谢途径的研究，主持，执行年限：2023.01-2024.12；

3. 国家自然科学基金（面上项目：31770119），假单胞菌PCA01经原儿茶酸途径和丛毛单胞菌GEN05经龙胆酸途径代谢3-甲基苯酚的分子机理研究, 主持，执行年限：2018.01-2021.12；

4. 微生物代谢国家重点实验室（上海交通大学）2015年开放课题（项目编号：MMLKF15-05），恶臭假单胞菌NCIMB9866分解代谢2,4-二甲基苯酚的机理研究, 主持，执行年限：2015.05-2017.04；

5. 国家自然科学基金（青年科学基金项目：31400068），潘多拉菌中氯苯代谢的两个基因簇的转录调控研究, 主持，执行年限：2015.01-2017.12；

6. 国家自然科学基金（面上项目：32070098），菌株Raoultella sp. YL01降解棉酚的代谢途径及分子机制研究，参与，执行年限：2021/01-2024/12；

7. 国家自然科学基金（面上项目：311870133），Rv1830通过调控RNA聚合酶活性参与分枝杆菌感染的作用机制，参与，执行年限：201901-202212；

8. 国家自然科学基金（面上项目：31271333），谷氨酸棒杆菌中3-羟基苯甲酸/龙胆酸代谢途径的调控研究，参与，执行年限：2013.01-2016.12。

代表性论文与著作（# Co-first author, * Corresponding author）

22. Jia-Xi Xiong, Ling-Shan Du, Na-Na Li, Xiu-Ting Wu, Yang Xiang, Sha Li, Lei Zou, Dongqi Liu, Duo Huang, Ze Feng Xie, Ying Wang, Jinhua Li, Jingcheng Dai, Dazhong Yan, Hong-Jun Chao*, Pigmentiphaga kullae CHJ604 improved the growth of tobacco by degrading allelochemicals and xenobiotics in continuous cropping obstacles. Journal of Hazardous Materials. 2024, 465, 133466.

21. Yang Xiang, Jia-Xi Xiong, Ze-Feng Xie, Duo Huang, Qi Song, Jing Wu, Dazhong Yan, Hong-Jun Chao*, The XylR/NtrC-type Regulator CbsR Positively Regulates Upstream Pathway of Chlorobenzene Degradation in Pandoraea pnomenusa. Journal of Applied Microbiology. 2023, 134(4), 1-12.

20. Ni-Hong Yao, Xi Liu, Chenyang Luo, Lei Zou, Jinhua Li, Jing Chen, Dazhong Yan, Hong-Jun Chao*, Methylhydroxylase encoded by mchAB gene is involved in methyl oxidation of m-cresol via Comamonas thiooxydans CHJ601. International Biodeterioration & Biodegradation. 2023. 179, 105583.

19. Ni-Hong Yao, Ya-Nan Du, Jia-Xi Xiong, Ying Xiao, Hang-Hang He, Ze-Feng Xie, Duo Huang, Qi Song, Jing Chen, DazhongYan, Hong-Jun Chao*, Microbial detoxification of 3,5-xylenol via a novel process with sequential methyl oxidation by Rhodococcus sp. CHJ602. Environmental Research. 2023. 220, 115258.

18. Shangbo Ning#, Hong-Jun Chao#, Shuangli Li, Rui Zhou, Lei Zou, Xu Zhang, Jun Liu, Dazhong Yan*, MojieDuan*, The Auto-inhibition Mechanism of Transcription Factor Ets-1 Induced by Phosphorylation on the Intrinsically Disordered Region. Computational and Structural Biotechnology Journal. 2022.22(1), 1132-1141.

17. Zou Lei, Sha Li, Nan Li, Shi-Long Ruan, Jing Chen, Jing Wu, Dazhong Yan and Hong-Jun Chao*, The Protocatechuate 3,4-Dioxygenase Solubility (PCDS) Tag Enhances the Expression and Solubility of Heterogenous Proteins in Escherichia coli. Frontiers in Microbiology. 2021, 12: 779541.

16. Hong-Jun Chao#, Dan Xue#, Wei jiang, Daosheng Li, Zhiquan Hu, Jianxiong Kang*, Dongqi Liu*, A low-voltage pulse-electrolysis method for the degradation of anthraquinone and azo dyes in chloride medium by anodic oxidation on Ti/IrO2-RuO2-SnO2 electrodes. Water Environment Research. 2020.5. 92(5), 779-788.

15. Hong-Jun Chao#, Xinran Zhang#, Wenqi Wang, Daosheng Li, Yongzheng Ren, Jianxiong Kang*, Dongqi Liu*, Evaluation of Carboxymethylpullulan-AlCl3 as a Coagulant for Water Treatment: a Case Study with Kaolin. Water Environment Research. 2020 Feb. 92(2), 302-309.

14. Hong-Jun Chao, Yuan-yuan Chen, Jing Wu, Da-Zhong Yan*, Ning-Yi Zhou, Complete Genome Sequence of a Chlorobenzene Degrader, Pandoraea pnomenusa MCB032. Current Microbiology. 2019 Nov, 76(11), 1235–1237.

13. He Fu, Jun-Jie Zhang, Ying Xu, Hong-Jun Chao*, Ning-Yi Zhou, Simultaneous biodegradation of three mononitrophenol isomers by a tailor-made microbial consortium immobilized in sequential batch reactors. Letters in Applied Microbiology. 2017, 64(2), 203-209.

12. Hong-Jun Chao, Yan-Fei Chen, Ti Fang, Ying Xu, Wei E Huang, and Ning-Yi Zhou*, HipH Catalyzes the Hydroxylation of 4-Hydroxyisophthalate to Protocatechuate in 2,4-Xylenol Catabolism by Pseudomonas putida NCIMB 9866. Applied and Environmental Microbiology. January 2016, 82(2):724-731.

11. Hong-Jun Chao, Bo Wu and Peihong Shen*, Overexpression of the Methanol Dehydrogenase Gene mxaF in Methylobacterium sp. MB200 Enhances L-Serine Production. Letters in Applied Microbiology. Oct. 2015, 61(4): 390–396.

10. Hongjun Chao and Ning-Yi Zhou*, Involvement of the Global Regulator GlxR in 3-Hydroxybenzoate and Gentisate Utilization by Corynebacterium glutamicum. Applied and Environmental Microbiology. July 2014, 80(14):4215-4225.

9. Hongjun Chao and Ning-Yi Zhou*, GenR, an IclR-type regulator, activates and represses the transcription of gen genes involved in 3-hydroxybenzoate and gentisate catabolism in Corynebacterium glutamicum. Journal of Bacteriology. April 2013, 195(7): 1598-1609.

8. Jin-Pei Wang, Wen-Mao Zhang, Hong-Jun Chao, Ning-Yi Zhou*. PnpM, a LysR-Type Transcriptional Regulator Activates the Hydroquinone Pathway in para-Nitrophenol Degradation in Pseudomonas sp. Strain WBC-3. Frontiers in Microbiology. 2017, 8: 1714.

7. Yi-Zhou Gao, Hong Liu, Hong-Jun Chao, and Ning-Yi Zhou*, Constitutive expression of Nag-like dioxygenase gene through an internal promoter in the 2-chloronitrobenzene catabolic gene cluster of Pseudomonas stutzeri ZWLR2-1. Applied and Environmental Microbiology. May 2016 82(12):3461-3470.

6. Wen-Mao Zhang, Jun-Jie Zhang, Xuan Jiang, Hongjun Chao and Ning-Yi Zhou*, Transcriptional Activation of Multiple Operons Involved in para-Nitrophenol Degradation by Pseudomonas sp. Strain WBC-3. Applied and Environmental Microbiology. 2015, 81(1): 220-230.

5. Yan-Fei Chen, Hongjun Chao and Ning-Yi Zhou*, The catabolism of 2,4-xylenol and p-cresol share the enzymes for the oxidation of para-methyl group in Pseudomonas putida NCIMB 9866, Applied Microbiology and Biotechnology, February 2014, 98(3): 1349-1356

4. Ying Xu, Bing Chen, Hongjun Chao and Ning-Yi Zhou*, mhpT encodes an active transporter involved in 3-(3-Hydroxyphenyl)propionate catabolism by Escherichia coli K-12. Applied and Environmental Microbiology, October 2013.79(20): 6362-6368.

3. Ying Xu, Song-He Wang, Hongjun Chao, Shuang-Jiang Liu, Ning-Yi Zhou*, Biochemical and Molecular Characterization of the Gentisate Transporter GenK in Corynebacterium glutamicum. PLoS ONE. 2012, 7 (7): e38701.

2. Peihong Shen, Hongjun Chao, Chengjian Jiang, Zhangde Long, Changhao Wang and Bo Wu*, Enhancing Production of L-Serine by Increasing the glyA Gene Expression in Methylobacterium sp. MB200, Applied Biochemistry and Biotechnology. 2010, 160 (3), 740-750.

1. Jihua Sun, Peihong Shen, Hongjun Chao and Bo Wu*, Isolation and identification of a new radiation-resistant bacterium Deinococcus guangxiensis sp. nov. and analysis of its radioresistant character, Acta Microbiologica Sinica, 2009, 49 (7), 918-924.

专利成果：

1. 晁红军，闫达中，吴菁，一种可降解3,5-二甲基苯酚的菌株及其应用，发明专利，专利号：ZL202110451188.1，申请日期：2021年04月25日，授权公布日：2022年03月18日。

2. 晁红军，闫达中，一种高效降解3-甲基苯酚的菌株及其筛选方法和应用，发明专利，专利号：ZL201910898166.2，申请日期：2019年09月02日，授权公布日：2021年01月22日。

研究生招生专业及方向

1. 0710生物学（学硕）

2.1007药学（学硕）

3. 105500药学（专硕）

4. 086000 生物与医药（专硕）